logo Insalogo Insa

Nanobioengineering

Presentation

Three workshops will be proposed in a research environment combining labrooms and a nanofabrication clean room:

 

1)     Single DNA Microarrays fabrication using soft-lithography and fluorescence detection

2)     Combined investigation (simulation/fluorescence) of a specific microfluidic system

3)     fabrication photolithography 2D/3D of microfluidic system.

 

 

Organisation:

 

A starting lecture of 10 h on technologies for biology will be dispend to students. Students (in groups) will be exposed to a specific scientific question (1,2 or 3) and will be asked to discover a technological solution for its investigation, to establish an experimental protocol (10 h), to implement these experiments (11 h), to discuss the results and the potential applications (2 h).

Objectives

At the end of this module, the student will have understood and be able to explain (main concepts):
 - Nanotechnological processes for the investigation, the sensing and the quantification of specific biomolecular interactions, the basis of all biosensing technologies
- The principles of some of these technologies: Fluorescence, Quartz Crystal Microbalance, soft lithography, surface biofunctionalization, single molecule assays, biochips, Atomic force microscopy
The student will be able to:
- Formulate nanoscale mechanisms and give precise examples of biomolecular specific interactions
- Master nanoscale techniques for biopatterning a substrate
- Master nanoscale techniques for transducing a molecular event into a measurable signal
- Analyze any kind of biosensor
- Perform a scientific experiment
- Implement nanotechnological processes
- Discuss and interpret results critically
- Bring together different concepts; extract them from their context in order to apply them in new situations

Needed prerequisite

Introduction to nanotechnologies
Scientific M1 in chemistry, biology or physics.

Form of assessment

The evaluation of outcome prior learning is made as a continuous training during the semester. According ot the teaching, the assessment will be different: as a written exam, an oral exam, a record, a written report, peers review...