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Systems and Synthetic Biology for biotechnologies


At the end of this module, the student will have understood and be able to explain (main concepts) :
- how Systems Biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole, especially Systems Biotechnology that allows optimal design and development of upstream to downstream bioprocesses by taking a systems approach  and Systems Medicine that considers diseases as "perturbations of networks", and transforms the way drugs are developed by targeting multiple components of networks and pathways perturbed in diseases;
- why Synthetic Biology, an emerging field, is located at the intersection of life science and engineering and is the application of the principles of engineering to the construction of life with desired properties in a rational and systematic way. What are the broad objectives of synthetic biology and their applications for biomedicine,  cheaper synthesis of biopharmaceuticals, sustainable chemical synthesis using efficient biotransformation, environment and energy
The student will be able to:
- consider a problem in biology by applying a systems biology approach and studying the mechanisms underlying complex biological processes as integrated systems of many interacting components.
- design and propose a synthetic biology approach to introduce novel functionality into engineered organisms for production purposes or for building new materials.
The student should be able to develop the most appropriate strategy and choose those tools which allow him to reach the goal of engineered biological systems with optimized biosynthetic pathways and develop efficient routes for producing pharmacologically active compounds, industrially important bulk chemicals, and liquid fuels for transportation

Form of assessment

The evaluation of outcome prior learning is made as a continuous training during the semester. According ot the teaching, the assessment will be different: as a written exam, an oral exam, a record, a written report, peers review...