Molecular biology
Presentation
Programme (detailed contents):
Lectures and tutorials :
Nucleic acids properties
Replication
Transcription
RNA processing
Regulator RNA and other non-coding RNA
Translation
Proteins folding, modifications, interactions, secretion and turnover
Lab work :
DNA extraction from bacteria and qualitative and quantitative analysis
Organisation:
Lectures and tutorials in parallel and lab work at the end of the UF
Main difficulties for students:
New concepts and weak background
Objectives
At the end of this module, the student will have understood and be able to explain (main concepts):
- Nucleic acids properties, genome organization and DNA replication
- Gene transcription and messenger RNA translation leading from DNA to proteins
- RNA processing and modifications
- Proteins folding, modifications, interactions, secretion and turnover
The student will be able to:
- Define and describe the main molecular elements enabling genome organization and gene expression.
The aim of this UF is to provide the molecular biology knowledge that is absolutely required to master the biotechnology tools. The student must be able to formulate, interpret and solve a molecular problem around the basic molecular processes allowing gene expression in order to master biotechnological tools and for optimizing and/or modifying living organisms of industrial interest.
Needed prerequisite
- Basics in biochemistry and microbiology
Form of assessment
The evaluation of outcome prior learning is made as a continuous training during the semester. According ot the teaching, the assessment will be different: as a written exam, an oral exam, a record, a written report, peers review...
Additional information
Nucleic Acids, DNA Replication, Gene Transcription, RNA Translation, Proteins metabolism