Molecular biology

Presentation

Programme (detailed contents):

Lectures and tutorials :

Nucleic acids properties

Replication

Transcription

RNA processing

Regulator RNA and other non-coding RNA

Translation

Proteins folding, modifications, interactions, secretion and turnover

Lab work :

DNA extraction from bacteria and qualitative and quantitative analysis

Organisation:

Lectures and tutorials in parallel and lab work at the end of the UF

Main difficulties for students:

New concepts and weak background

Objectives

At the end of this module, the student will have understood and be able to explain (main concepts):

- Nucleic acids properties, genome organization and DNA replication

-   Gene transcription and messenger RNA translation leading from DNA to proteins

- RNA processing and modifications

- Proteins folding, modifications, interactions, secretion and turnover

The student will be able to:

- Define and describe the main molecular elements enabling genome organization and gene expression.

The aim of this UF is to provide the molecular biology knowledge that is absolutely required to master the biotechnology tools. The student must be able to formulate, interpret and solve a molecular problem around the basic molecular processes allowing gene expression in order to master biotechnological tools and for optimizing and/or modifying living organisms of industrial interest.

Needed prerequisite

- Basics in biochemistry and microbiology

Form of assessment

The evaluation of outcome prior learning is made as a continuous training during the semester. According ot the teaching, the assessment will be different: as a written exam, an oral exam, a record, a written report, peers review...

Additional information

Nucleic Acids, DNA Replication, Gene Transcription, RNA Translation, Proteins metabolism