Genetic and Enzymatic engineering

Objectifs

At the end of this module, the student will have understood and be able to explain (main concepts):

Enzyme engineering

Understand the bioinformatics methods and computational tools used for i) genome assembly and annotation, ii) genome and protein sequence and structure analysis  iii) comprehension of enzyme mechanism and engineering.

Genetic engineering

Understand the main approaches used for genetic engineering and synthetic biology. Understand the methodology used for scientific article search in data bases, for writing a scientific literature review and presenting a critical analysis of scientific articles.

The student will be able to:

Enzymatic engineering

Describe the methods used for bioinformatics analysis of genome and protein structures (sequence alignment and molecular modelling and graphism tools). Apply computational methods to structure-activity relationship studies and enzyme engineering.

Genetic engineering

Use of bibliographic database for scientific article search.

Construct and write a scientific literature review

Know and describe various approaches and methods entering in the field of genetic engineering.

Pré-requis

Structural biochemistry and molecular biology

Évaluation

L’évaluation des acquis d’apprentissage est réalisée en continu tout le long du semestre. En fonction des enseignements, elle peut prendre différentes formes : examen écrit, oral, compte-rendu, rapport écrit, évaluation par les pairs…